Method and System for Prediction of Post-Stenting Hemodynamic Metrics for Treatment Planning of Arterial Stenosis

摘要

A method and system for prediction of post-stenting hemodynamic metrics for treatment planning of arterial stenosis is disclosed. A pre-stenting patient-specific anatomical model of the coronary arteries is extracted from medical image data of a patient Blood flow is simulated in the pre-stenting patient-specific anatomical model of the coronary arteries with a modified pressure-drop model that simulates an effect of stenting on a target stenosis region used to compute a pressure drop over the target stenosis region. Parameter values for the modified pressure-drop model are set without modifying the pre-stenting patient-specific anatomical model of the coronary arteries. A predicted post-stenting hemodynamic metric for the target stenosis region, such as fractional flow reserve (FFR), is calculated based on the pressure-drop over the target stenosis region computed using the modified pressure-drop model.

主权项

1. A method for predicting a post-stenting hemodynamic metric for a coronary artery stenosis from pre-stenting medical image data, comprising:
extracting a pre-stenting patient-specific anatomical model of the coronary arteries from medical image data of a patient; simulating blood flow in the pre-stenting patient-specific anatomical model of the coronary arteries with a modified pressure-drop model for computing a pressure drop over a target stenosis region in the pre-stenting patient-specific anatomical model of the coronary arteries, wherein the modified pressure-drop model simulates an effect of stenting on the target stenosis region; and calculating a predicted post-stenting hemodynamic metric for the target stenosis region based on the pressure-drop over the target stenosis region computed using the modified pressure-drop model.