发明名称 EGFR AND ROS1 IN CANCER EGFR ROS1
摘要 <p>The present disclosure provides methods of that include detecting in a biological sample from a patient having or suspected of having cancer the presence of a polypeptide having ROS1 kinase activity or a polynucleotide encoding the same and detecting in the biological sample the presence of a mutant EGFR polypeptide or a polynucleotide encoding the same. In some aspects, the disclosure provides methods of treating a patient for cancer that include determining that a biological sample from a tumor in the patient includes a polypeptide having ROS1 kinase activity or a polynucleotide encoding the same and a mutant EGFR polypeptide or a polynucleotide encoding the same and administering to the patient a therapeutically effective amount of a ROS1 inhibitor and an EGFR inhibitor, thereby treating the patient for cancer.</p>
申请公布号 HK1206056(A1) 申请公布日期 2015.12.31
申请号 HK20150106509 申请日期 2015.07.08
申请人 CELL SIGNALING TECHNOLOGY INC. 发明人 CROSBY, KATHERINE, ELEANOR;MCGUINNESS RIMKUNAS, VICTORIA;SILVER, MATTHEW, REN;HAACK, HERBERT
分类号 C12N 主分类号 C12N
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