发明名称 NANOPARTICLES FOR DRUG DELIVERY
摘要 The invention provides nanoparticles, methods for making nanoparticles, and methods for using nanoparticles. An important attribute of a drug delivery system is its ability to allow for spatial and temporal regulated drug release, thereby minimizing side effects and improving therapeutic efficacy of conventional pharmaceuticals. Iron oxide nanoparticles (NPs), specifically Fe304 nanoparticles, possess many appropriate qualities that make them a viable choice for drug delivery.
申请公布号 US2015374849(A1) 申请公布日期 2015.12.31
申请号 US201414766726 申请日期 2014.02.07
申请人 KNIPP Ralph J.;NANTZ Michael H.;UNIVERSITY OF LOUISVILLE RESEARCH FOUNDATION, INC. 发明人 KNIPP Ralph J.;NANTZ Michael H.
分类号 A61K47/48 主分类号 A61K47/48
代理机构 代理人
主权项 1. A therapeutic magnetic nanoparticle, or a salt thereof, comprising a magnetic nanoparticle covalently bonded to one or more -L-D groups wherein D is a residue of a therapeutic agent and L is a linker capable of undergoing an intramolecular cyclization.
地址 Louisville KY US