GLUCOSE-SENSITIVE NANOPARTICLE FOR CANCER DIAGNOSIS AND THERAPY

摘要

Disclosed are glucose-sensitive nanoparticles which includes a phenylboronic acid derivative and a biocompatible polymer, and is prepared as an amphiphilic conjugate having chemical binding between the phenylboronic acid derivative and the biocompatible polymer. The use of the composition can effectively collect glucose in the cancer tissue, thereby simultaneously performing diagnosis and therapy of cancer.

主权项

1. A composition for diagnosis, therapy, or simultaneous diagnosis and therapy of cancer, the composition containing, as active ingredients, (a) a biocompatible polymer, and (b) a conjugate bound to the biocompatible polymer and including a phenyl boronic acid derivative.