| 发明名称 |
GRAM-POSITIVE BACTERIA SPECIFIC BINDING COMPOUNDS |
| 摘要 |
The present invention provides improved binding compounds capable of specifically binding Gram-positive bacteria. Binding compounds are provided that are fully human, enabling therapeutic applications in human individuals. |
| 申请公布号 |
US2015376266(A1) |
申请公布日期 |
2015.12.31 |
| 申请号 |
US201514728826 |
申请日期 |
2015.06.02 |
| 申请人 |
Genentech, Inc. ;AIMM Therapeutics B.V. |
发明人 |
BEAUMONT Tim;KWAKKENBOS Mark Jeroen;BROWN Eric J.;MORISAKI John Hiroshi;HAZENBOS Wouter L.W.;MARIATHASAN Sanjeev;KAJIHARA Kimberly;XIA Yi |
| 分类号 |
C07K16/12 |
主分类号 |
C07K16/12 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. An isolated antibody comprising:
(a) a heavy chain CDR1 sequence RFAMS (SEQ ID NO:1), and (b) a heavy chain CDR2 sequence SINNGNNPYYARSVQY (SEQ ID NO:2), and (c) a heavy chain CDR3 sequence DHPSSGWPTFDS (SEQ ID NO:3). |
| 地址 |
South San Francisco CA US |
