发明名称 NOVEL ESTERIFIED CELLULOSE ETHERS OF LOW VISCOSITY
摘要 Esterified cellulose ethers which comprise (i) aliphatic monovalent acyl groups or (ii) groups of the formula —C(O)—R—COOA, wherein R is a divalent aliphatic or aromatic hydrocarbon group and A is hydrogen or a cation, or (iii) a combination of aliphatic monovalent acyl groups and groups of the formula —C(O)—R—COOA, which have a viscosity of up to 2.33 mPa·s, measured as a 2.0 wt % solution of the esterified cellulose ether in 0.43 wt % aqueous NaOH at 20° C., and which have a viscosity of up to 13 mPao·s, measured as a 10 wt % solution of the esterified cellulose ether in acetone at 20° C. are useful for preparing solid dispersions comprising drugs.
申请公布号 US2015374831(A1) 申请公布日期 2015.12.31
申请号 US201414766997 申请日期 2014.02.28
申请人 DOW GLOBAL TECHNOLOGIES LLC 发明人 Brackhagen Meinolf;Guillaudeu Steven J.;Grasman Nicholas S.;Petermann Oliver;Schmitt Robert L.;Sprehe Matthias
分类号 A61K47/38;C08B13/00 主分类号 A61K47/38
代理机构 代理人
主权项 1. An esterified cellulose ether comprising (i) aliphatic monovalent acyl groups or (ii) groups of the formula —C(O)—R—COOA, wherein R is a divalent aliphatic or aromatic hydrocarbon group and A is hydrogen or a cation, or (iii) a combination of aliphatic monovalent acyl groups and groups of the formula —C(O)—R—COOA, having a viscosity of up to 2.33 mPa·s, measured as a 2.0 wt % solution of the esterified cellulose ether in 0.43 wt % aqueous NaOH at 20° C., and having a viscosity of up to 13 mPa·s, measured as a 10 wt % solution of the esterified cellulose ether in acetone at 20° C.
地址 Midland MI US