发明名称 |
NOVEL ESTERIFIED CELLULOSE ETHERS OF LOW VISCOSITY |
摘要 |
Esterified cellulose ethers which comprise (i) aliphatic monovalent acyl groups or (ii) groups of the formula —C(O)—R—COOA, wherein R is a divalent aliphatic or aromatic hydrocarbon group and A is hydrogen or a cation, or (iii) a combination of aliphatic monovalent acyl groups and groups of the formula —C(O)—R—COOA, which have a viscosity of up to 2.33 mPa·s, measured as a 2.0 wt % solution of the esterified cellulose ether in 0.43 wt % aqueous NaOH at 20° C., and which have a viscosity of up to 13 mPao·s, measured as a 10 wt % solution of the esterified cellulose ether in acetone at 20° C. are useful for preparing solid dispersions comprising drugs. |
申请公布号 |
US2015374831(A1) |
申请公布日期 |
2015.12.31 |
申请号 |
US201414766997 |
申请日期 |
2014.02.28 |
申请人 |
DOW GLOBAL TECHNOLOGIES LLC |
发明人 |
Brackhagen Meinolf;Guillaudeu Steven J.;Grasman Nicholas S.;Petermann Oliver;Schmitt Robert L.;Sprehe Matthias |
分类号 |
A61K47/38;C08B13/00 |
主分类号 |
A61K47/38 |
代理机构 |
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代理人 |
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主权项 |
1. An esterified cellulose ether
comprising (i) aliphatic monovalent acyl groups or (ii) groups of the formula —C(O)—R—COOA, wherein R is a divalent aliphatic or aromatic hydrocarbon group and A is hydrogen or a cation, or (iii) a combination of aliphatic monovalent acyl groups and groups of the formula —C(O)—R—COOA, having a viscosity of up to 2.33 mPa·s, measured as a 2.0 wt % solution of the esterified cellulose ether in 0.43 wt % aqueous NaOH at 20° C., and having a viscosity of up to 13 mPa·s, measured as a 10 wt % solution of the esterified cellulose ether in acetone at 20° C. |
地址 |
Midland MI US |