METHODS FOR TREATING PSORIASIS AND PSORIATIC ARTHRITIS

摘要

Methods, agents and compositions thereof for treating psoriatic arthritis (PsA) and psoriasis (Ps) are encompassed herein, as are methods for identifying pathogenic dysbiosis in a subject, the presence of which is a positive indicator of risk for developing PsA or of the presence of PsA in a subject with arthritic symptoms.

主权项

1. A method for treating a subject afflicted with psoriasis, the method comprising administering to the subject a therapeutically effective amount of a sample comprising a fecal transplant isolated from a healthy donor or a therapeutically effective amount of a composition comprising at least one purified bacterial species of a genera of Akkermansia, Ruminococcus, Pseudobutyrivibrio, Coprococcus, and Coprobacillus, wherein administering the fecal transplant or the composition comprising the at least one purified bacterial species treats the subject afflicted with psoriasis.