发明名称 Anti-Viral Azide Containing Compounds
摘要 Methods of using azide-modified biomolecules, such as fatty acids, carbohydrates and lipids, to treat a plant, an insect or an animal infected with a virus or to inhibit infectivity of a virus, such as the human immunodeficiency virus, are provided. Also provided are methods of labeling a virus, such as human immunodeficiency virus, with an azide-modified biomolecule, such as a fatty acid, a carbohydrate, or an isoprenoid lipid. Also, provided are methods of tracking a virus in vivo, with an azide-modified biomolecule, such as a fatty acid, a carbohydrate, or an isoprenoid lipid. The azide-modified biomolecules may be combined with a pharmaceutically acceptable excipient to produce a pharmaceutical composition, optionally containing another anti-viral agent and/or a delivery agent, such as a liposome.
申请公布号 US2015374723(A1) 申请公布日期 2015.12.31
申请号 US201514831220 申请日期 2015.08.20
申请人 Life Technologies Corporation ;The Johns Hopkins University 发明人 Agnew Brian;Graham David;Singh Upinder;Grecian Scott
分类号 A61K31/655;A61K38/21;A61K31/7088;A61K45/06 主分类号 A61K31/655
代理机构 代理人
主权项 1. A pharmaceutical composition comprising an azide-modified fatty acid or pharmaceutically acceptable salt thereof and a pharmaceutically acceptable excipient.
地址 Carlsbad CA US