发明名称 |
T7 RNA POLYMERASE VARIANTS AND METHODS OF USING THE SAME |
摘要 |
The present invention relates to T7 RNA polymerase variants with improved affinity for 2′-modified nucleotides compared to the wildtype as well as methods for their production and methods of using them. The present invention also relates to the 2′-modified RNA molecules produced according to the methods of the invention. |
申请公布号 |
US2015376581(A1) |
申请公布日期 |
2015.12.31 |
申请号 |
US201214439133 |
申请日期 |
2012.10.29 |
申请人 |
TECHNISCHE UNIVERSITÄT DORTMUND |
发明人 |
BRAKMANN Susanne;IBACH Jenny |
分类号 |
C12N9/12;C12P19/34 |
主分类号 |
C12N9/12 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
Dortmund DE |