| 发明名称 |
FGFR1 AGONISTS AND METHODS OF USE |
| 摘要 |
The invention provides FGFR1 agonists, including agonistic anti-FGFR1 antibodies, and methods of using the same. |
| 申请公布号 |
US2015376283(A1) |
申请公布日期 |
2015.12.31 |
| 申请号 |
US201514754229 |
申请日期 |
2015.06.29 |
| 申请人 |
GENENTECH, INC. |
发明人 |
Sonoda Junichiro;Wu Yan |
| 分类号 |
C07K16/28;A61K39/395;C07K16/40;A61K45/06 |
主分类号 |
C07K16/28 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A method of treating a metabolic disease or condition in an individual, comprising administering to the individual an effective amount of an anti-fibroblast growth factor receptor-1 (FGFR1) antibody, wherein the antibody binds to peptide #26 KLHAVPAAKTVKFKCP (SEQ ID NO: 28) or peptide #28 FKPDHRIGGYKVRY (SEQ ID NO: 29) and wherein the antibody is a human, humanized, or chimeric antibody. |
| 地址 |
South San Francisco CA US |
