| 发明名称 |
Inhibitors of Branched-Chain-Aminotransferase-1 (BCAT1) for the Treatment of Brain Tumors |
| 摘要 |
Described is a compound capable of reducing or inhibiting (a) the biological activity of branched-chain-aminotrans-ferase-1 (BCATI) or (b) the expression of the gene encoding BCATI for use in a method of treating a neoplasia. A preferred compound is 1-(aminomethyl)cyclohexaneacetic acid (gabapentin). |
| 申请公布号 |
US2015374800(A1) |
申请公布日期 |
2015.12.31 |
| 申请号 |
US201514752280 |
申请日期 |
2015.06.26 |
| 申请人 |
Deutsches Krebsforschungszentrum |
发明人 |
RADLWIMMER Bernhard;TOENJES Martje;BARBUS Sebastian;LICHTER Peter |
| 分类号 |
A61K38/45;C07K16/40;C12N15/113;A61K31/195 |
主分类号 |
A61K38/45 |
| 代理机构 |
|
代理人 |
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| 主权项 |
|
| 地址 |
Heidelberg DE |
