| 发明名称 |
PYRIMIDINE COMPOUNDS FOR THE TREATMENT OF CANCER |
| 摘要 |
Described are compounds of Formula I or Formula II: wherein: ring A is a 5- or 6-membered heteroaryl group; dashed lines are optional double bonds; X is N or O; Y is a carbon atom or an S or N heteroatom in ring A in any suitable location; and substituents are as given herein. Compositions containing the same and methods of using the same in treating cancers such as acute lymphoblastic leukemia are also described. |
| 申请公布号 |
EP2852579(A4) |
申请公布日期 |
2015.12.30 |
| 申请号 |
EP20130793925 |
申请日期 |
2013.05.21 |
| 申请人 |
THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL |
发明人 |
WANG, XIAODONG;ZHANG, WEIHE;KIREEV, DMITRI;ZHANG, DEHUI;MCIVER, ANDREW |
| 分类号 |
C07D239/32;A61K31/505;A61P35/00;C07D239/48;C07D401/04;C07D401/06;C07D401/12;C07D401/14;C07D403/04;C07D403/12;C07D405/04;C07D405/12;C07D405/14;C07D409/12;C07D409/14;C07D417/04;C07D417/14 |
主分类号 |
C07D239/32 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
