发明名称 RECEPTOR TYROSINE KINASE INHIBITOR-RESISTANT ANTICANCER DRUG COMPOSITION COMPRISING 3,4,5-TRIHYDROXYBENZOIC ACID, DERIVATIVE THEREOF OR SALT THEREOF AS ACTIVE INGREDIENT
摘要 The present invention relates to a composition for preventing or treating a cancer resistant to a target anticancer drug, the composition including, as an active ingredient, a 3,4,5-trihydroxybenzoic acid (gallic acid) compound or a derivative thereof which specifically inhibits cancer cells that exhibit resistance to an anticancer drug targeting receptor tyrosine kinase. Since the 3,4,5-trihydroxybenzoic acid (gallic acid) compound or a derivative thereof specifically kills cancer cells that exhibit resistance to an anticancer drug targeting receptor tyrosine kinase, cancer diseases that are resistant to a receptor tyrosine kinase inhibitor such as gefitinib can be prevented or treated.
申请公布号 WO2015199454(A1) 申请公布日期 2015.12.30
申请号 WO2015KR06464 申请日期 2015.06.25
申请人 YONSEI UNIVERSITY WONJU INDESTRY-ACADEMIC COOPERATION FOUNDATION 发明人 JEONG, YANG SIK;KIM, KI WOO;MO, SANG HYUN
分类号 A61K31/192;A61K31/19;A61P35/00 主分类号 A61K31/192
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