摘要 |
The present invention relates to the use SHIP inhibitors to induce expression of granulocyte colony stimulating factor (G-CSF) in a subject, thereby promoting expansion of hematopoietic and mesenchymal stem cells. The present invention generally relates to new uses of SHIP inhibitors for therapeutic purposes. More particularly, the present invention relates to the use of SHIP inhibitors, including, without limitation, SHIP1 and/or pan-SHIP1/2 inhibitors, for the inhibition of SHIP to induce expression of granulocyte colony stimulating factor (G-CSF) to treat various-diseases or conditions. |