发明名称 |
BETA-GLUCAN IMMUNOTHERAPEUTIC METHODS |
摘要 |
This disclosure describes, in one aspect, a method for identifying &bgr;-glucan binding to immune cells of a subject. Generally, the method includes obtaining a blood sample from the subject, the blood sample comprising immune cells, adding soluble &bgr;-glucan to at least a portion of the blood sample and incubating the mixture under conditions allowing the soluble &bgr;-glucan to bind to the immune cells, and detecting soluble &bgr;-glucan bound to the immune cells. In another aspect, this disclosure describes a method that generally includes identifying the subject as a low binder of &bgr;-glucan, and co-administering to the subject a soluble &bgr;-glucan and an antibody preparation capable of converting the subject from a low binder to a high binder. |
申请公布号 |
EP2844262(A4) |
申请公布日期 |
2015.12.30 |
申请号 |
EP20130784589 |
申请日期 |
2013.03.14 |
申请人 |
BIOTHERA, INC. |
发明人 |
GROSSMAN, WILLIAM, J.;ANTONYSAMY, MARY, A.;WALSH, RICHARD, M.;NELSON, MARIANA, I.;BOSE, NANDITA;DANIELSON, MICHAEL, E.;MICHEL, KYLE, S. |
分类号 |
A61K31/716;C07K16/18;G01N33/53 |
主分类号 |
A61K31/716 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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