| 发明名称 |
PHARMACEUTICAL COMPOSITION COMPRISING A BI-CYCLIC COMPOUND AND METHOD FOR STABILIZING THE BI-CYCLIC COMPOUND |
| 摘要 |
<p>Disclosed is a method for stabilizing a pharmaceutically active bi-cyclic compound of formula (I):
comprising the step of: admixing the same with a polyol and/or a fatty acid ester other than glyceride and a composition obtained by the method. In addition a soft gelatin capsule formulation of the compound of formula (I) obtained by incorporating the compound in a soft gelatin capsule shell comprising gelatin and a polyol plasticizer.</p> |
| 申请公布号 |
EP1984027(B1) |
申请公布日期 |
2015.12.30 |
| 申请号 |
EP20070707565 |
申请日期 |
2007.01.23 |
| 申请人 |
R-TECH UENO, LTD.;SUCAMPO AG |
发明人 |
HIRATA, RYU;HARADA, YASUHIRO;UENO, RYUJI |
| 分类号 |
A61K47/14;A61K9/08;A61K9/48;A61K31/352;A61K31/353;A61K31/382;A61K31/4741;A61K47/10;A61K47/12;A61K47/26;A61K47/36 |
主分类号 |
A61K47/14 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
