摘要 |
Compounds having a structure of Structure I: or a pharmaceutically acceptable salt, tautomer, or stereoisomer thereof, wherein R1, R2, R3, R4, R5, J1, J2, X, Z, n1 and n2 are as defined herein, and wherein at least one of R1, R2 or R3 is an alkyl, alkenyl, aryl or aralkyl ester, are provided. Uses of such compounds for treatment of various indications, including prostate cancer, as well as methods of treatment involving such compounds are also provided. |
申请人 |
BRITISH COLUMBIA CANCER AGENCY BRANCH;THE UNIVERSITY OF BRITISH COLUMBIA UNIVERSITY-INDUSTRY LIAISON OFFICE |
发明人 |
MAWJI, NASRIN R.;WANG, JUN;BANUELOS, CARMEN ADRIANA;ANDERSEN, RAYMOND JOHN;FERNANDEZ, JAVIER GARCIA;SADAR, MARIANNE DOROTHY |