摘要 |
The present invention provides a drug containing a compound having Trk-inhibiting activity as an active ingredient in prophylaxis and/or therapy for Trk-related diseases such as pain, pruritus, lower urinary tract dysfunction, asthma, allergic rhinitis, inflammatory bowel disease or Chagas disease. A compound represented by the general formula (I):
wherein all symbols represent the same meanings as described in the specification,
a salt thereof, an N-oxide thereof, a solvate thereof or a prodrug thereof is useful as a drug component having Trk-inhibiting activity in prophylaxis and/or therapy of diseases such as pain, pruritus, lower urinary tract dysfunction, asthma, allergic rhinitis, inflammatory bowel disease or Chagas disease. |
申请人 |
ONO PHARMACEUTICAL CO., LTD. |
发明人 |
TAKEUCHI, JUN;ITADANI, SATOSHI;HASHIMURA, KAZUYA;IKURA, MASAHIRO;HIGASHINO, MASATO;YASUHIRO, TETSUYA;NAGAURA, TAKESHI |