发明名称 OXABICYCLOHEPTANES AND OXABICYCLOHEPTENES, THEIR PREPARATION AND USE
摘要 The present invention relates to a compound having the structure defined herein or a salt thereof, enantiomer or zwitterion, wherein bond α is absent; Rand Rare together =O; Ris O(CH)Ror OR, where Ris C-Caryl, and where Ris C-Calkyl, substituted C-Calkyl, C-Calkenyl, C-Calkynyl, substituted C-Caryl,orRiswhere X is NR, where each Ris C-Calkyl, C-Chydroxyalkyl, C-Calkenyl or C-Calkynyl; or Rand Rare different from each other and each is OH orRand Rare together =O; and Rand Reach is H. The invention also relates to a process for preparing the same, to a pharmaceutical composition comprising the same and to the use of the compound for the treatment of tumors.
申请公布号 EA022311(B1) 申请公布日期 2015.12.30
申请号 EA20110070288 申请日期 2009.07.30
申请人 LIXTE BIOTECHNOLOGY, INC. 发明人 KOVACH JOHN, S.;JOHNSON FRANCIS
分类号 C07C49/613;C07C49/00 主分类号 C07C49/613
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