发明名称 |
MULTISPECIFIC ANTIBODY CONSTRUCTS |
摘要 |
The present disclosure relates to a multi-specific antibody molecule comprising or consisting of: a) a polypeptide chain of formula (I): VH-CH1-X-V1; and b) a polypeptide chain of formula (II): VL-CL-Y-V2 and pharmaceutical formulations comprising, for example for use in treatment. The disclosure also provides polynucleotide sequences encoding said multispecific antibody molecules, vectors comprising the polynucleotides and host cells comprising said vectors and/or polynucleotide sequences. There is a provided a method of expressing a multispecific antibody molecule of the present disclosure from a host cell. |
申请公布号 |
CA2951609(A1) |
申请公布日期 |
2015.12.30 |
申请号 |
CA20152951609 |
申请日期 |
2015.06.25 |
申请人 |
UCB BIOPHARMA SPRL |
发明人 |
BHATTA, PALLAVI;DAVE, EMMA;HEYWOOD, SAM PHILIP;HUMPHREYS, DAVID PAUL |
分类号 |
C07K16/46;C12N15/13;C12P21/08 |
主分类号 |
C07K16/46 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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