发明名称 2-(3-PYRIDINYL)-1H-BENZIMIDAZOLE DERIVATIVE COMPOUND AND MEDICINE CONTAINING SAME
摘要 Provided is a compound represented by general formula (1) or a salt thereof, and a medicine containing the compound or the salt. (In the formula, R1 represents a hydrogen atom or CO2Ra; R2 represents a hydrogen atom, a halogen atom, or CO2Ra; R3 represents a hydrogen atom or a C1–10 hydroxyalkyl group; R4 represents a hydrogen atom, a hydroxy group, or a C1–10 alkoxy group; R5 represents a C1–5 chain alkyl group in which the hydrogen atoms are optionally substituted with halogen atoms, a C3–5 cyclic alkyl group in which the hydrogen atoms are optionally substituted with halogen atoms, a C1–5 hydroxyalkyl group, or an o-, p-, or m-halobenzyl group; A represents CH or a nitrogen atom; X1 and X3 independently represent hydrogen atoms or halogen atoms; X2 represents a hydrogen atom, a halogen atom, or a nitrile group; at least one of X1, X2, and X3 represents a halogen atom; and Ra independently represents a C1–10 alkyl group.)
申请公布号 WO2015199205(A1) 申请公布日期 2015.12.30
申请号 WO2015JP68431 申请日期 2015.06.25
申请人 NIHON MEDI-PHYSICS CO., LTD.;KYOTO UNIVERSITY;NATIONAL HOSPITAL ORGANIZATION 发明人 IZAWA AKIHIRO;AKAMA KEI;OKUMURA YUKI;FUKUI YURIE;KOBASHI NOBUYA;ABE TSUTOMU;DOI YOSHIHIRO;IKENAGA MIHO;SAJI HIDEO;KIMURA HIROYUKI;NARUSE MITSUHIDE
分类号 C07D401/14;A61K31/4439;A61K51/00;A61P35/00 主分类号 C07D401/14
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