发明名称 ORALLY ADMINISTERED ADSORBENT, THERAPEUTIC AGENT FOR RENAL DISEASE, AND THERAPEUTIC AGENT FOR LIVER DISEASE
摘要 An object of the present invention is to provide an orally administered adsorbent capable of adsorbing large quantities of tryptophan or indoxyl sulfate in the presence of bile acid. The problem can be solved by an orally administered adsorbent comprising spherical active carbon having bulk density from 0.30 to 0.46 g/mL, specific surface area determined by the Brunauer-Emmett-Teller (BET) method of not less than 2000 m 2 /g, total acid group content of less than 0.30 meq/g, pore volume of pore diameter from 20 to 10,000 nm of not more than 0.21 mL/g; and a micropore volume ratio (Vm) of not less than 1.0, determined by Formula (1): Vm = (V 2.0 -V 1.1 )/(V 1.1 -V 0.64 ) (1) [in Formula (1), V 2.0 , V 1.1 , and V 0.64 are cumulative pore volumes of pore diameters not greater than 2.0 nm, not greater than 1.1 nm, and not greater than 0.64 nm, respectively, calculated by the SF method from nitrogen adsorbed quantity].
申请公布号 EP2959906(A1) 申请公布日期 2015.12.30
申请号 EP20140754624 申请日期 2014.02.24
申请人 KUREHA CORPORATION 发明人 SONOBE, NAOHIRO;WAKAHOI, TAKASHI;AKITA, TAKAHIRO
分类号 A61K33/44;A61P1/16;A61P13/12;A61P39/02;B01J20/20;C01B31/10 主分类号 A61K33/44
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