发明名称 |
ANTIBODIES FOR TREATING AND PROPHYLAXIS OF ALZHEIMER'S DISEASE AND USE THEREOF |
摘要 |
Described are the use of an antibody is that specifically binds to a N-terminal epitope of Aβ for manufacturing a preparation for treating Alzheimer's disease and similar diseases in which the regime administered to a patient depends on the ApoE genotype of the patient and also a humanized form of a 3D6 antibody that specifically binds to a N-terminal epitope of Aβ, a pharmaceutical composition comprising said antibody and an isolated nucleic acid encoding said antibody. |
申请公布号 |
EA022307(B1) |
申请公布日期 |
2015.12.30 |
申请号 |
EA20100000644 |
申请日期 |
2008.10.17 |
申请人 |
JANSSEN SCIENCES IRELAND UC;WYETH LLC |
发明人 |
BLACK RONALD;EKMAN LARS;LIEBERBURG IVAN;GRUNDMAN MICHAEL;CALLAWAY JIM;GREGG KEITH, M.;JACOBSEN JACK, STEVEN;GILL DAVINDER;TCHISTIAKOVA LIOUDMILA;WIDOM ANGELA |
分类号 |
A61K39/00;C07K16/18 |
主分类号 |
A61K39/00 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|