Drug products in the form of modified release formulations comprising the drug substance (-)-(3aR,4S,7aR)-4-Hydroxy-4m-tolylethynyl-octahydro-indole-1-carboxylic acid methyl ester (AFQ056), as well as processes for making such drug products are provided. The drug products are useful in treating patients with Parkinson's disease and exhibiting L-dopa induced dyskinesia.
申请公布号
SG11201509178T(A)
申请公布日期
2015.12.30
申请号
SGT11201509178
申请日期
2014.06.11
申请人
NOVARTIS AG
发明人
GALLI, BRUNO;THOMA, HUBERT;GRANDEURY, ARNAUD;SPICKERMANN, DIRK;PUTZBACH, KARSTEN;MOLL, KLAUS-PETER;UFER, MIKE;GLANTZMANN, JEAN-MARIE;MUELLER-ZSIGMONDY, MARTIN