Phenylalkyl sulfamate compound and muscle relaxant composition comprising the same

摘要

The present invention relates to novel phenylalkyl sulfamate compounds, a method for preventing or treating a disease associated with muscle spasm. The present invention ensures the enhancement of muscle relaxation activity essential for alleviation of muscle spasm, such that it is promising for preventing or treating various diseases associated with muscle spasm.

主权项

1. A compound represented by the following formula 1 or pharmaceutically acceptable salt thereof:wherein R1 and R2 are each independently selected from the group consisting of hydrogen, C1-C5 alkyl group and C6-C10 aryl group or R1 and R2 together with the carbon atom to which they attach form C5-C6 cycloalkyl group; R3, R4, R5, R6 and R7 are each independently selected from the group consisting of hydrogen, halogen, C1-C5 alkyl group, nitro group and unsubstituted or C1-C3 alkyl-substituted amine group; R8 and R9 are each independently hydrogen or C1-C3 alkyl group; n and m are each independently integer of 0-2.