Method and fuel cell for electrochemical measurement of analyte concentration in vivo

摘要

The invention relates to a method for the electrochemical measurement of an analyte concentration in vivo, comprising a fuel cell with which the analyte to be measured is reacted catalytically with an enzyme contained in an enzyme layer and which supplies an electrical voltage, dependent on the analyte concentration to be measured, beween an anode and a cathode, which voltage is measured. In the catalytic reaction of the analyte to be measured in the enzyme layer, a product is generated which, as fuel of the fuel cell, oxidizes on the anode and is reduced on the cathode. The invention further relates to a fuel cell for such a method.

主权项

1. A fuel cell, comprising:
an anode and a cathode, the cathode having a surface made of a different material than that of the anode; an enzyme layer containing an enzyme for the catalytic conversion of a substance occurring in the human body, the enzyme layer forming a diffusion path to the anode and to the cathode for a fuel product generated by catalytic conversion of the substance, the fuel cell adapted to oxidize the fuel product on the anode and reduce it on the cathode; and wherein the substance for the catalytic conversion is an analyte to be measured and wherein the enzyme layer contacts the anode and the cathode.