| 发明名称 | Cancer therapy | ||
| 摘要 | The present invention provides agents useful in the treatment of cancer, as well as systems for identifying and/or characterizing such agents, and systems for identifying and/or characterizing patient populations responsive to particular agents. | ||
| 申请公布号 | US9220723(B2) | 申请公布日期 | 2015.12.29 |
| 申请号 | US201113805621 | 申请日期 | 2011.06.23 |
| 申请人 | BRANDEIS UNIVERSITY | 发明人 | Ren Ruibao;Cuiffo Benjamin |
| 分类号 | C12N15/113;A61K31/713;A61K31/336 | 主分类号 | C12N15/113 |
| 代理机构 | Choate, Hall & Stewart LLP | 代理人 | Choate, Hall & Stewart LLP ;Jarrell, JD Brenda Herschbach |
| 主权项 | 1. A method of treating cancer by administering to a patient in need thereof an agent that directly inhibits activity of a RAS palmitoyl-acyl transferase and reduces palmitoylation of NRAS, wherein the agent blocks a RAS palmitoylation site. | ||
| 地址 | Waltham MA US | ||