| 摘要 |
A pulverulent crystalline maltitol composition, is characterized in that it has a laser volume mean diameter between 10 and 150 μm; in that it has a maltitol content between 80 and 99.9% by weight; in that at least 50% by weight of its particles flow through a sieve having a cut-off threshold of 2000 μm according to a test A1; in that at least 35% by weight of its particles flow through a sieve having a cut-off threshold of 2000 μm according to a test A2; and in that it includes from 0.1 to 20% by weight of at least one water-insoluble anti-caking agent, the anti-caking agent having a hygroscopicity, determined according to the test B, between 2.5 and 25%. This composition is not subject to caking, and finds applications in the food and pharmaceutical fields. |
| 主权项 |
1. A puiverant crystalline maltitol composition, comprising:
a maltitol content between 80 and 99.9 wt %; at least 50 wt % of particles of the composition flow through a sieve having a cut-off threshold of 2000 μm according to a test A1, said test A1 comprising the steps of: introducing 100g of said composition into a low-density polyethylene sachet with internal dimensions of 10 cm ×5 cm, which are obtained by heat-sealing low-density polyethylene films having a thickness of 100 μm along three sides, hermetically heat-sealing the sachet comprising said composition, laying the sachet flat in climatic chamber over seven days and subjecting the sachet to a succession of four cycles:
(i) 3.5 hours at 23° C. in 83% relative humidity (or RH),(ii) 0.5 h of transition,(iii) 3.5 hours at 40° C. in 92% RH, and(iv) 0.5 h of transition, and opening the sachet at the end of the seven days and pouring said composition over a sieve having a mesh of 2000μm, vibrating for 10 seconds at an amplitude setting of 5over an agate pocket and ball mill, wherein said wt % of particles are those that pass through the 2000 μm sieve; at least 35 wt % of particles of the composition flow through a sieve having a cut-off threshold of 2000 μm according to a test A2, said test A2 being identical to said test A1 except that the sachet pressurized by placing a 2 kg weight on the sachet during said seven days in said climatic chamber; from 0.1 to 20 wt % of an anti-caking agent selected from the group consisting of fumed silica, sodium aluminosilicate, anhydrous tricalcium phosphate and dehydrated potato starch, and mixtures thereof, said anti-caking agent having a hygroscopicity at 80% RH, determined according to the test B, between 2.5 and 25%, said test B comprising the steps of: subjecting a less than 10 mg sample of said anti-caking agent to a cycle of relative humidity (PI) at 20° C., with nitrogen as a carrier gas, in equipment comprising a differential microbalance which makes it possible to quantify a change in weight of a sample relative to a reference when said sample is subjected to various climatic conditions, said cycle comprising:
(i) 5 hours at 20% RH,(ii) an increase from 20% to 70% RH over 30 minutes,(iii) holding for 5 hours at 70% RH,(iv) increasing from 70% to 80% RH over 30 minutes, and(v) holding for 5 hours at 80%, wherein hygroscopicity at 80% RH is according to the following equation: (m80−m20)/m20×100 expressed in %, where m20 is the mass of the sample at the end of the 5 hours at 20% RH and m80 is the mass of the sample at the end of the 5 hours at 80% RH; and wherein said composition has a laser volume mean diameter between 10 and 150 μm. |
