| 发明名称 | Method for detecting nucleosomes | ||
| 摘要 | The invention relates to a method for detecting and measuring the presence of mono-nucleosomes and oligo-nucleosomes and the use of such measurements for the detection and diagnosis of disease. | ||
| 申请公布号 | US9222937(B2) | 申请公布日期 | 2015.12.29 |
| 申请号 | US201214239782 | 申请日期 | 2012.08.31 |
| 申请人 | Singapore Volition Pte. Limited | 发明人 | Micallef Jacob Vincent |
| 分类号 | G01N33/53;G01N33/68 | 主分类号 | G01N33/53 |
| 代理机构 | Foley & Lardner LLP | 代理人 | Foley & Lardner LLP |
| 主权项 | 1. A method for detecting nucleosomes in a sample which comprises the steps of: (i) contacting the sample with three or more binding agents which bind to different or separate nucleosome epitopes; (ii) detecting or quantifying the binding of said multiple binding agents to nucleosomes in the sample; and (iii) using the presence or degree of such binding as a measure of the presence of nucleosomes in the sample. | ||
| 地址 | Singapore SG | ||