| 发明名称 |
Treponema pallidum triplet antigen |
| 摘要 |
A Treponema pallidum triplet antigen construct is disclosed which includes three Treponema pallidum antigens (TP15, TP17, and TP47), as well as a ten amino acid leader sequence (tag 261) and human copper zinc superoxide dismutase (hSOD). This construct is optimized for in vitro diagnosis of syphilis infection. Plasmids containing DNA encoding the triplet antigen, host cells, production methods, detection methods, and kits are also disclosed. |
| 申请公布号 |
US9221884(B2) |
申请公布日期 |
2015.12.29 |
| 申请号 |
US201414193530 |
申请日期 |
2014.02.28 |
| 申请人 |
Ortho-Clinical Diagnostics, Inc. |
发明人 |
Zheng Jian;Yura Renee;Yang Jianping |
| 分类号 |
C07K14/20;G01N33/569;G01N33/571 |
主分类号 |
C07K14/20 |
| 代理机构 |
|
代理人 |
Timian Susan J. |
| 主权项 |
1. A Treponema pallidum triplet antigen consisting of the amino acid sequence of SEQ ID NO: 12. |
| 地址 |
Raritan NJ US |
