| 主权项 |
1. A continuous bioreactor culturing device comprising:
(a) a 3-dimensional lattice-shaped scaffold having x, y and z Cartesian axes thereby providing an overall shape to the scaffold, the scaffold formed by a matrix of layered, interconnected growth surfaces spaced in the x, y and z Cartesian axes at regular intervals thereby providing a plurality of interconnected open spaces all arranged orthogonally in a 3-dimensional matrix and parallel to the x, y and z Cartesian axes of the scaffold disposed between the spaced interconnected growth surfaces, the interconnected open spaces allowing a fluid to pass continuously through the scaffold parallel to and in the direction of at least one of the x, y and z Cartesian axes, the scaffold including a first cylindrical support on a first side of the scaffold that couples with a bioreactor fluid inlet and a second cylindrical support on a second side of the scaffold that couples with a bioreactor fluid outlet allowing the first side to serve as an inlet for the fluid and the second side to serve as an outlet for the fluid as the fluid passes through the scaffold, and (b) fluid distribution means, including the bioreactor fluid inlet and the bioreactor fluid outlet, disposed at the inlet and at the outlet of the scaffold, respectively, where the bioreactor fluid inlet includes multiple inlet distribution conduits that collectively and continuously distribute the fluid through and around the open spaces of the first side and the bioreactor fluid outlet includes multiple outlet conduits that collectively and continuously collect the fluid from the second side;wherein all of the interconnected growth surfaces are aligned with each other in relation to the x, y and z Cartesian axes, and the plurality of interconnected open spaces of the scaffold have a substantially cubic shape. |
