Bone graft materials and methods

摘要

Compositions, materials, methods and kits for bone grafting are described. In some embodiments, a bone graft composition includes about 15% to about 20% by weight collagen, about 55% to about 70% by weight bioactive glass, and about 15% to about 30% by weight a calcium phosphate. The bioactive glass and the calcium phosphate together are about 80% to about 85% by weight of the bone graft composition. In some embodiments, a bone graft composition includes a collagen matrix and a plurality of bioactive glass particulates dispersed throughout the collagen matrix. The collagen matrix is about 20% to about 60% by weight of the bone graft composition, and the bioactive glass is about 40% to about 80% of the bone graft composition. In some embodiments, a majority of the bioactive glass particulates are about 53 μm to about 425 μm in size.

主权项

1. A bone graft composition comprising:
about 15% to about 20% by weight collagen; about 55% to about 70% by weight bioactive glass, the bioactive glass having a size within a range of about 53 μm to about 425 μm in size, at least 85% of the bioactive glass having a size within a range of 212 μm to 425 μm in size; and about 15% to about 30% by weight calcium phosphate.