摘要 |
<p>Provided herein are Heteroaryl Compounds having the following structure: (I) wherein R1, R2, L, X, Y, Z, Q, A and B are as defined herein, compositions comprising an effective amount of a Heteroaryl Compound and methods for treating or preventing cancer, inflammatory conditions, immunological conditions, metabolic conditions and conditions treatable or preventable by inhibition of a kinase pathway comprising administering an effective amount of a Heteroaryl Compound to a patient in need thereof.</p> |
申请人 |
SIGNAL PHARMACEUTICALS, LLC |
发明人 |
MORTENSEN, DEBORAH SUE;MEDEROS, MARIA MERCEDES DELGADO;SAPIENZA, JOHN JOSEPH;ALBERS, RONALD J.;LEE, BRANDEN G.;HARRIS, ROY LEONARD, III;SHEVLIN, GRAZIELLA ISABEL;HUANG, DEHUA;SCHWARZ, KIMBERLY LYN;PACKARD, GARRICK K.;PARNES, JASON SIMON;PAPA, PATRICK WILLIAM;TEHRANI, LIDA, RADNIA;PERRIN-NINKOVIC, SOPHIE;RIGGS, JENNIFER R. |