| 主权项 |
1. A method of treating or preventing a metalloenzyme-mediated disease or disorder in or on a plant comprising contacting a composition comprising a compound of Formula I with the plant or seeds; wherein MBG is optionally substituted tetrazolyl, optionally substituted triazolyl, optionally substituted oxazolyl, optionally substituted pyrimidinyl, optionally substituted thiazolyl, or optionally substituted pyrazolyl; R1 is H, halo, alkyl or haloalkyl; R2 is H, halo, alkyl or haloalkyl; R3 is independently H, alkyl, nitro, cyano, haloalkyl, alkoxy, halo, haloalkoxy, alkenyl, haloalkenyl, cycloalkyl, halocycloalkyl, alkynyl, haloalkynyl, thioalkyl, SF3, SF6, SCN, SO2R6, —C(O)-alkyl, —C(O)OH, —C(O)O-alkyl, C(O)H, CH═N—O-alkyl, —CH═N—O-arylalkyl; R4 is aryl, heteroaryl or cycloalkyl optionally substituted with 0, 1, 2 or 3 independent R3; R5 is alkyl, haloalkyl, cycloalkyl, C2-C8 alkenyl, C2-C8 alkynyl, aryl, heteroaryl, arylalkyl, or heteroarylalkyl, each optionally substituted with 0, 1, 2 or 3 independent R3; R6 is alkyl, aryl, substituted aryl, heteroaryl or substituted heteroaryl; R7 is H, alkyl, —Si(R8)3, —P(O)(OH)2, —CH2—O—P(O)(OH)2, or —C(O)-alkyl optionally substituted with amino; R8 is independently alkyl or aryl; R9 is independently H, alkyl, halo, or haloalkyl; and X is O or S. |
