SILK-BASED NANOIMPRINTING

摘要

Protein-protein imprinting of silk fibroin is introduced as a rapid, high-fidelity, and/or high-throughput method for the fabrication of nanoscale structures in silk films, through controlled manipulation of heat and/or pressure. High resolution imprinting on conformal surfaces is also demonstrated.

主权项

1. A composition comprising:
a first silk fibroin material comprising a predetermined nanostructure fabricated thereon; wherein the first silk fibroin material has a first beta sheet content and a first glass transition temperature (Tg1); a second silk fibroin material, having a second beta sheet content and a second glass transition temperature (Tg2); wherein the first silk fibroin material is in close contact with the second silk fibroin material, such that the predetermined nanostructure on the first fibroin material is substantially replicated onto the second silk fibroin material to produce an inverse imprint of the predetermined nanostructure.