发明名称 NOVEL ESTERIFIED CELLULOSE ETHERS OF VERY HIGH MOLECULAR WEIGHT
摘要 Esterified cellulose ethers which comprise (i) groups of the formula —C(O)—R—COOA or (ii) a combination of aliphatic monovalent acyl groups and groups of the formula —C(O)—R—COOA, wherein R is a divalent aliphatic or aromatic hydrocarbon group and A is hydrogen or a cation, which have a viscosity of up 50 mPa·s, measured as a 10 wt % solution of the esterified cellulose ether in acetone at 20° C., and a weight average molecular weight Mw of at least 220,000 Dalton, or which have a viscosity of up 100 mPa·s, measured as a 10 wt % solution of the esterified cellulose ether in acetone at 20° C., and a weight average molecular weight Mw of at least 310,000 Dalton are useful for preparing solid dispersions comprising drugs.
申请公布号 US2015368366(A1) 申请公布日期 2015.12.24
申请号 US201414766609 申请日期 2014.02.28
申请人 DOW GLOBAL TECHNOLOGIES LLC 发明人 PETERMANN Oliver;BRACKHAGEN Meinolf;SPREHE Matthias
分类号 C08B13/00;A61K9/48 主分类号 C08B13/00
代理机构 代理人
主权项 1. An esterified cellulose ether comprising (i) groups of the formula —C(O)—R—COOA or (ii) a combination of aliphatic monovalent acyl groups and groups of the formula —C(O)—R—COOA, wherein R is a divalent aliphatic or aromatic hydrocarbon group and A is hydrogen or a cation, having a viscosity of up to 50 mPa·s, measured as a 10 wt % solution of the esterified cellulose ether in acetone at 20° C., and having a weight average molecular weight Mw of at least 220,000 Dalton.
地址 Midland MI US