发明名称 |
NOVEL ESTERIFIED CELLULOSE ETHERS OF VERY HIGH MOLECULAR WEIGHT |
摘要 |
Esterified cellulose ethers which comprise (i) groups of the formula —C(O)—R—COOA or (ii) a combination of aliphatic monovalent acyl groups and groups of the formula —C(O)—R—COOA, wherein R is a divalent aliphatic or aromatic hydrocarbon group and A is hydrogen or a cation, which have a viscosity of up 50 mPa·s, measured as a 10 wt % solution of the esterified cellulose ether in acetone at 20° C., and a weight average molecular weight Mw of at least 220,000 Dalton, or which have a viscosity of up 100 mPa·s, measured as a 10 wt % solution of the esterified cellulose ether in acetone at 20° C., and a weight average molecular weight Mw of at least 310,000 Dalton are useful for preparing solid dispersions comprising drugs. |
申请公布号 |
US2015368366(A1) |
申请公布日期 |
2015.12.24 |
申请号 |
US201414766609 |
申请日期 |
2014.02.28 |
申请人 |
DOW GLOBAL TECHNOLOGIES LLC |
发明人 |
PETERMANN Oliver;BRACKHAGEN Meinolf;SPREHE Matthias |
分类号 |
C08B13/00;A61K9/48 |
主分类号 |
C08B13/00 |
代理机构 |
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代理人 |
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主权项 |
1. An esterified cellulose ether
comprising (i) groups of the formula —C(O)—R—COOA or (ii) a combination of aliphatic monovalent acyl groups and groups of the formula —C(O)—R—COOA, wherein R is a divalent aliphatic or aromatic hydrocarbon group and A is hydrogen or a cation, having a viscosity of up to 50 mPa·s, measured as a 10 wt % solution of the esterified cellulose ether in acetone at 20° C., and having a weight average molecular weight Mw of at least 220,000 Dalton. |
地址 |
Midland MI US |