| 发明名称 |
ANTIBODIES AGAINST EPIDERMAL GROWTH FACTOR RECEPTOR (EGFR) AND USES THEREOF |
| 摘要 |
Anti-EGFR antibodies, therapeutic compositions comprising combinations of anti-EGFR antibodies, as well as methods for using such antibodies and compositions to treat EGFR-related disorders (e.g., cancers), are disclosed. |
| 申请公布号 |
US2015368347(A1) |
申请公布日期 |
2015.12.24 |
| 申请号 |
US201514847297 |
申请日期 |
2015.09.08 |
| 申请人 |
MERRIMACK PHARMACEUTICALS, INC. |
发明人 |
BUKHALID Raghida;FELDHAUS Michael;KING Anne;KOHLI Neeraj;KRAULAND Eric;KEARNS Jeffrey David;LUGOVSKOY Alexey A.;NIELSEN Ulrik |
| 分类号 |
C07K16/28;A61K39/395;A61K9/00 |
主分类号 |
C07K16/28 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A monoclonal antibody which binds EGFR extracellular domain and comprises heavy chain CDR1, CDR2, and CDR3 sequences as set forth in SEQ ID NOs: 1, 2, and 3, respectively, and light chain CDR1, CDR2, and CDR3 sequences as set forth in SEQ ID NOs: 4, 5 and 6, respectively. |
| 地址 |
Cambridge MA US |
