| 发明名称 |
METHODS FOR INCREASING IMMUNOGLOBULIN A LEVELS |
| 摘要 |
Methods for increasing immunoglobulin A (IgA) levels in a subject having a deficiency thereof are provided herein by administering to the subject an agent that inhibits CXCL13 activity, such as an anti-CXCL13 or an anti-CXCR5 antibody. Further provided are methods for treating an inflammatory disorder in a subject deficient for IgA by administering to the subject an agent that inhibits CXCL13 activity. |
| 申请公布号 |
US2015368332(A1) |
申请公布日期 |
2015.12.24 |
| 申请号 |
US201414765162 |
申请日期 |
2014.01.31 |
| 申请人 |
VACCINEX, INC. |
发明人 |
Zauderer Maurice;Yoshida Masaru;Yamamoto Koji;Smith Ernest S. |
| 分类号 |
C07K16/24 |
主分类号 |
C07K16/24 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A method for increasing immunoglobulin A (IgA) levels in a subject having a deficiency thereof, said method comprising administering to said subject an effective amount of an agent that inhibits CXCL13 activity. |
| 地址 |
Rochester NY US |
