发明名称 |
CELL SORTING SYSTEM USING MICROFABRICATED COMPONENTS |
摘要 |
A MEMS-based cell sorter is disclosed, which uses a novel combination of features to accomplish the cell sorting using a microfabricated cell sorting valve housed in a disposable cartridge. The features include an interposer that provides fluid communication between the microfluidic passages in the silicon substrate and a plurality of fluid reservoirs in the cartridge, including a sample, sort and waste reservoir The disposable cartridge may include other features that assist in the handling of small volumes of fluids, such as a siphon region in the sort reservoir and funnel-shaped regions in the sample and waste reservoirs. A mixing mechanism may be provided for stirring the contents of the sample reservoir. |
申请公布号 |
US2015367346(A1) |
申请公布日期 |
2015.12.24 |
申请号 |
US201514638495 |
申请日期 |
2015.03.04 |
申请人 |
Owl biomedical, Inc. |
发明人 |
FOSTER John S.;Martinez Nicholas C.;Grummitt Daryl;Peters Ralf-Peter;Peth Christian;Nagel Markus |
分类号 |
B01L3/00 |
主分类号 |
B01L3/00 |
代理机构 |
|
代理人 |
|
主权项 |
1. A cell sorting system for sorting target particles from a fluid sample, comprising:
a cell sorting valve microfabricated on a surface of a silicon substrate, with microfabricated channels leading from the cell sorting valve, wherein the cell sorting valve separates the target particles from non-target material; a disposable cartridge containing a sample reservoir, a sort reservoir and a waste reservoir; and an interposer that provides fluid communication between the microfabricated channels in the silicon substrate and the reservoirs in the disposable cartridge. |
地址 |
Goleta CA US |