发明名称 |
Pharmaceutical compositions comprising a GPG oligodeoxynucleotide and cyclic di-GMP |
摘要 |
The present invention relates to pharmaceutical compositions comprising an immunostimulatory amount of at least two immunopotentiators, wherein a first immunopotentiator is a non-methylated cytidyl guanosyl oligodeoxynucleotide (CpG ODN) and a second immunopotentiator is 3 ',5 '-cyclic diguanylic acid (c-di-GMP), and a pharmaceutically acceptable carrier. The invention also relates to the use of such pharmaceutical compositions for the induction of an immune response against tumor-specific antigens. Also the invention relates to their use in in situ tumor-destruction therapy and to such pharmaceutical compositions for use in the treatment of a mammal suffering from cancer. |
申请公布号 |
AU2014280133(A1) |
申请公布日期 |
2015.12.24 |
申请号 |
AU20140280133 |
申请日期 |
2014.06.13 |
申请人 |
INTERVET INTERNATIONAL B.V. |
发明人 |
SCHRIER, CARLA CHRISTINA;BROK DEN, MARTIJN;ADEMA, GOSSE |
分类号 |
A61K31/7084;A61K31/7088;A61P35/00;A61P37/04 |
主分类号 |
A61K31/7084 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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