发明名称 |
METHODS AND MATERIALS FOR THERAPEUTIC DELIVERY |
摘要 |
Methods for preparing a supramolecular therapeutic agent delivery assembly are provided. A hydrophilic precursor, a hydrophibic precursor, and an aromatic diamine precursor may be combined to form an amphiphilic block co-polymer. The block co-polymer may undergo a cross-linking polymerization process and a therapeutic agent may be incorporated into the resulting supramolecular assembly. The supramolecular assembly may comprise HT, PHT, HA, and/or PHA materials. |
申请公布号 |
US2015366972(A1) |
申请公布日期 |
2015.12.24 |
申请号 |
US201414311223 |
申请日期 |
2014.06.20 |
申请人 |
International Business Machines Corporation |
发明人 |
BODAY Dylan J.;GARCIA Jeannette M.;HEDRICK James L.;WOJTECKI Rudy J. |
分类号 |
A61K47/34;C08G73/06 |
主分类号 |
A61K47/34 |
代理机构 |
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代理人 |
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主权项 |
1. A method of preparing a supramolecular therapeutic agent delivery assembly comprising:
providing a first precursor, a second precursor, and a third precursor; performing a ring opening polymerization to form a block co-polymer; cross-linking the block co-polymer by performing a PHT or PHA polymerization process to form a supramolecular assembly; and incorporating a therapeutic agent into the supramolecular assembly. |
地址 |
Armonk NY US |