发明名称 |
PHARMACEUTICAL LIPID COMPOSITIONS |
摘要 |
The present invention relates to a particulate composition containing; a) 5 to 90% of at least one phosphatidyl choline component b) 5 to 90% of at least one diacyl glycerol component, at least one tocopherol, or mixtures thereof, and c) 1 to 40% of at least one non-ionic stabilising amphiphile, where all parts are by weight relative to the sum of the weights of a+b+c and where the composition contains particles of at least one non-lamellar phase structure or forms particles of at least one non-lamellar phase structure when contacted with an aqueous fluid. The invention additionally relates to pharmaceutical formulations containing such compositions, methods for their formation and methods of treatment comprising their administration. |
申请公布号 |
US2015366970(A1) |
申请公布日期 |
2015.12.24 |
申请号 |
US201514715757 |
申请日期 |
2015.05.19 |
申请人 |
CAMURUS AB |
发明人 |
JOHNSSON Markus;TIBERG Fredrik |
分类号 |
A61K47/24;A61K38/22;A61K38/28;A61K38/26;A61K31/05;A61K38/31 |
主分类号 |
A61K47/24 |
代理机构 |
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代理人 |
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主权项 |
1. A composition comprising;
a) 5 to 90% of at least one phosphatidyl choline component; b) 5 to 90% of at least one diacyl glycerol component, at least one tocopherol, or mixtures thereof; c) 1 to 40% of at least one non-ionic stabilising amphiphile, wherein all parts are by weight relative to the sum of the weights of a+b+c and wherein the composition forms particles of at least one non-lamellar phase structure when contacted with an aqueous fluid. |
地址 |
Lund SE |