发明名称 TREATMENT OF A SAMPLE VESSEL
摘要 Provided herein is technology related to the chemical modification and purification of DNA. Specifically, the technology provides methods for performing a bisulfite conversion reaction on small amounts of single-stranded, fragmented DNA and performing the subsequent desulfonation and purification steps on magnetic beads, and methods for treating sample vessels prior to recovery of converted DNA from the vessel.
申请公布号 US2015368636(A1) 申请公布日期 2015.12.24
申请号 US201414764716 申请日期 2014.01.30
申请人 EXACT SCIENCES CORPORATION 发明人 Allawi Hatim;Lidgard Graham P.;Aizenstein Brian;Hunt Oliver;Zutz Tobias
分类号 C12N15/10;C12Q1/68;C07H21/04 主分类号 C12N15/10
代理机构 代理人
主权项 1. A method for recovering nucleic acid from a sample vessel, comprising: i) binding nucleic acid in a sample vessel; ii) recovering at least a portion of said nucleic acid from said sample vessel; wherein said sample vessel is exposed to a solution comprising at least one of bovine serum albumin or casein prior to said recovering.
地址 Madison WI US