ANTI-STAPHYLOCOCCAL ANTIBODIES

摘要

This disclosure generally relates to antibodies or fragments thereof which interact with the bacterial protein MprF. The disclosure further discloses antibodies, which bind to specific extracellular motifs of MprF. The disclosure further relates to therapeutics comprising MprF-specific antibodies and methods of treatment using MprF-specific antibodies or fragments thereof.

主权项

1. An antibody or antibody fragment specific for a polypeptide comprising SEQ ID NO.: 1, or an orthologue thereof, wherein said antibody or antibody fragment increases the susceptibility of a pathogen to a cationic antimicrobial peptide.