发明名称 |
Recombinant microorganisms exhibiting increased flux through a fermentation pathway |
摘要 |
The invention provides methods of increasing the production of fermentation products by increasing flux through a fermentation pathway by optimising enzymatic reactions. In particular, the invention relates to identifying enzymes and/or co-factors involved in metabolic bottlenecks in fermentation pathways, and fermenting a CO-comprising substrate with a recombinant carboxydotrophic Clostridia microorganism adapted to exhibit increased activity of the one or more of said enzymes, or increased availability of the one or more of said co-factors, when compared to a parental microorganism. |
申请公布号 |
AU2014274838(A1) |
申请公布日期 |
2015.12.24 |
申请号 |
AU20140274838 |
申请日期 |
2014.06.05 |
申请人 |
LANZATECH NEW ZEALAND LIMITED |
发明人 |
KOPKE, MICHAEL;MUELLER, ALEXANDER PAUL |
分类号 |
C12P7/04;C12P7/06;C12P7/16 |
主分类号 |
C12P7/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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