| 发明名称 |
POSITIVELY CHARGED POLYSACCHARIDES FOR RNA TRANSFECTION |
| 摘要 |
A complex includes RNA and a positively charged modified polysaccharide selected from starch, amylose, amylopectin, galactan, chitosan, or dextrin. The complex can be formed into a pharmaceutical composition. The complex can be used in methods for RNA transfection, gene therapy and treatment of a disease, disorder or condition. The positively charged modified polysaccharide can be used in connection with RNA transfection into cells. |
| 申请公布号 |
US2015366979(A1) |
申请公布日期 |
2015.12.24 |
| 申请号 |
US201414765790 |
申请日期 |
2014.02.05 |
| 申请人 |
B. G. NEGEV TECHNOLOGIES AND APPLICATIONS LTD. ;RAMOT AT TEL-AVIV UNIVERSITY LTD |
发明人 |
KOST Joseph;GOLDBART Riki;TRAITEL Tamar;LEWIS AMAR Eliz;LIFSHIZ Rinat;PEER Dan |
| 分类号 |
A61K47/48;C12N15/113;A61K41/00 |
主分类号 |
A61K47/48 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A complex comprising RNA and a positively charged modified polysaccharide, said polysaccharide being selected from the group consisting of starch, amylose, amylopectin, galactan and dextrin. |
| 地址 |
Beer Sheva IL |
