| 摘要 |
<p>The disclosure relates to PI3K inhibitors of the formula (I) in which all of the variables are as defined in the specification, to their preparation, to their medical use, in particular to their use in the treatment of cancer and neurodegenerative disorders, and to medicaments comprising them. A representative purine derivative is: 8-(6-Fluoro-1H-indol-4-yl)-2-((S)-3-methylmorpholin-4-yl)-6-((R)-3-methyl-morpholin-4-yl)-9H-purine.</p> |
