| 发明名称 |
NOVEL COMPOUNDS |
| 摘要 |
The present invention relates to a tris salt of 8-chloro-3-pentyl-3,7-dihydro-1H-purine-2,6-dione of Formula (A):;;corresponding manufacture processes, pharmaceutical formulations containing and uses of the aforementioned compound in therapy, particularly in treatment of diseases where under-activation of the HM74A receptor contributes to the disease or where activation of the receptor will be beneficial. |
| 申请公布号 |
US2015366870(A1) |
申请公布日期 |
2015.12.24 |
| 申请号 |
US201514840549 |
申请日期 |
2015.08.31 |
| 申请人 |
GlaxoSmithKline LLC |
发明人 |
ESKEN Holly;NORTON Beth Adams |
| 分类号 |
A61K31/522;A61K31/133 |
主分类号 |
A61K31/522 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A method for treating stroke in a human subject in need thereof, comprising administering to said subject a therapeutically effective amount of a compound which is 8-chloro-3-pentyl-3,7-dihydro-1H-purine-2,6-dione tris(hydroxymethyl)aminomethane (Formula (IA): |
| 地址 |
Wilmington DE US |
