发明名称 |
NOVEL BETA-ALANINE DERIVATIVES, PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF, AND PHARMACEUTICAL COMPOSITION COMPRISING SAME AS ACTIVE INGREDIENT |
摘要 |
The present invention relates to a beta-alanine derivative, pharmaceutically acceptable salts thereof, and a pharmaceutical composition including the same as an active ingredient. The novel beta-alanine derivative and pharmaceutically acceptable salts thereof according to the present invention may effectively inhibit the activity of DGAT1, which is an enzyme serving as a catalyst in the final step of the synthesis of neutral lipids, to thereby be effectively used as a pharmaceutical composition for preventing or treating various lipid metabolism-related disorders selected from the group consisting of obesity, dyslipidemia, fatty liver, insulin resistance syndrome, and hepatitis. |
申请公布号 |
EP2842938(A4) |
申请公布日期 |
2015.12.23 |
申请号 |
EP20130781273 |
申请日期 |
2013.04.25 |
申请人 |
KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY;HANDOK PHARMACEUTICALS CO., LTD. |
发明人 |
AHN, JIN HEE;H. S. PAGIRE;RHEE, SANG DAL;KIM, KI YOUNG;JUNG, WON HOON;BAE, MYUNG-AE;SONG, JIN SOOK;KIM, KWANG-ROK;KWAK, HYUN JUNG |
分类号 |
C07C233/25;A61K31/16;A61P1/16;A61P3/04;C07C237/04;C07C237/22;C07C271/22;C07D209/42;C07D213/82;C07D231/14;C07D239/26;C07D261/10;C07D263/34;C07D277/56;C07D417/12 |
主分类号 |
C07C233/25 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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