发明名称 NOVEL BETA-ALANINE DERIVATIVES, PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF, AND PHARMACEUTICAL COMPOSITION COMPRISING SAME AS ACTIVE INGREDIENT
摘要 The present invention relates to a beta-alanine derivative, pharmaceutically acceptable salts thereof, and a pharmaceutical composition including the same as an active ingredient. The novel beta-alanine derivative and pharmaceutically acceptable salts thereof according to the present invention may effectively inhibit the activity of DGAT1, which is an enzyme serving as a catalyst in the final step of the synthesis of neutral lipids, to thereby be effectively used as a pharmaceutical composition for preventing or treating various lipid metabolism-related disorders selected from the group consisting of obesity, dyslipidemia, fatty liver, insulin resistance syndrome, and hepatitis.
申请公布号 EP2842938(A4) 申请公布日期 2015.12.23
申请号 EP20130781273 申请日期 2013.04.25
申请人 KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY;HANDOK PHARMACEUTICALS CO., LTD. 发明人 AHN, JIN HEE;H. S. PAGIRE;RHEE, SANG DAL;KIM, KI YOUNG;JUNG, WON HOON;BAE, MYUNG-AE;SONG, JIN SOOK;KIM, KWANG-ROK;KWAK, HYUN JUNG
分类号 C07C233/25;A61K31/16;A61P1/16;A61P3/04;C07C237/04;C07C237/22;C07C271/22;C07D209/42;C07D213/82;C07D231/14;C07D239/26;C07D261/10;C07D263/34;C07D277/56;C07D417/12 主分类号 C07C233/25
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