发明名称 METHODS OF TREATING TTP WITH IMMUNOGLOBULIN SINGLE VARIABLE DOMAINS AND USES THEREOF
摘要 <p>The present invention is based on the finding that administration of polypeptides comprising at least one Immunoglobulin single variable domains against vWF to human TTP patients provides a significant decrease in the time to response. The invention provides a polypeptide comprising at least one immunoglobulin single variable domain (ISVD) against von Willebrand Factor (vWF) for use in treating a vWF-related disease in a human in need thereof. The invention further relates to dosage unit forms, kits and medical uses for treating TTP.</p>
申请公布号 WO2015193326(A1) 申请公布日期 2015.12.23
申请号 WO2015EP63493 申请日期 2015.06.16
申请人 ABLYNX NV 发明人 DUBY, CHRISTIAN
分类号 A61K38/36;A61P7/00 主分类号 A61K38/36
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